Hipec and Pipac are both treatments used in oncology, but they are quite different in terms of application and purpose.

1. HIPEC (Hyperthermic Intraperitoneal Chemotherapy): HIPEC is a procedure used to treat advanced abdominal cancers, particularly those that have spread within the abdomen. During HIPEC, heated chemotherapy drugs are circulated throughout the abdomen after the visible tumors have been removed through surgery. The goal is to kill any remaining cancer cells and prevent recurrence.

2. PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy): PIPAC is a newer technique that involves delivering chemotherapy drugs directly into the abdominal cavity in the form of an aerosol under pressure. This is done through laparoscopic surgery. PIPAC is typically used for peritoneal metastases, which are cancerous spread to the lining of the abdominal cavity.

In summary, HIPEC is used after surgical removal of visible tumors to kill remaining cancer cells, while PIPAC is a minimally invasive technique for delivering chemotherapy directly into the abdominal cavity for peritoneal metastases. Each has its own indications and considerations based on the patient’s condition and the type of cancer being treated.

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